Industrial enzyme reference database
Assay methods, regulatory status and safety data for industrial enzymes, with sources.
Enzyme Atlas compiles the public record on commercial enzymes: official and literature assay methods, structures and sequences, approvals by market, toxicology, suppliers and markets. Each entry links to its primary source.
From enzyme to submission
The routine work of an enzyme QC lab or regulatory team, in one place.
Compare every published method for an enzyme: official standard or literature, substrate, readout, conditions and unit definition.
See GRAS notices, EU and other national lists, and how each market's regulator handles enzymes, linked to the regulator's own page.
Fit kinetics, trend lot QC and estimate shelf life in the Workbench. Convert units and work out doses in Lab tools.
Report Studio drafts development and validation reports, procedures, stability reports and dossier sections, ready for expert review and export to Word.
What each record contains
Every enzyme record carries the same tabs, so the data for one enzyme is in one place.
Built for the people who work with enzymes
Whether you run the assay, sign off the dossier or sell the product.
Choose and validate activity methods.
- Official and literature methods side by side
- Validation protocols and reports
- Unit conversion and dosing
Know the status before the question comes.
- Status by market with source links
- Weekly alerts on new approvals
- Dossier and CTD section drafts
Start from what's known.
- Structures, sequences and kinetics
- Application notes with references
- Safety and toxicology summaries
See the market around each enzyme.
- Who makes what, with brands and patents
- Market size by industry
- Company results
How the data is sourced
Every value can be traced back to the document it came from.
Regulator pages, standards bodies, DOIs and PubMed IDs. Click through and check.
Anything not yet checked against its source carries a visible tag until it is.
Methods are summarised in our own words with the exact designation. Buy the current edition from the issuing body.
Calculators and Report Studio run in your browser. Nothing you type is sent anywhere.
Plans
Start free. Upgrade when you need reports, alerts and exports.
Everything in Explorer, plus Report Studio, Workbench, regulatory records, weekly alerts, a watchlist and CSV export.
Get ProfessionalProfessional for the whole site, shared records, priority method additions and API access.
Talk to usLook up an enzyme
The enzyme list, profiles and method overview are open without an account. Request access for reports, alerts and exports.
Explore enzymes
Pick an industry or enzyme class, then open any enzyme for its assays, structures, sequences and regulatory status.
Regulatory status by market
Global framework coverage: how each of the world's markets regulates enzymes, and what its regulator looks for. Click a market for details. Per-enzyme records start with the US and EU; open an enzyme in Explore to see them. Entries tagged “group summary” come from their bloc or framework and are not yet checked country by country. This is research, not legal advice.
| Market | Regulator | How food enzymes are regulated | Coverage |
|---|
Markets
Market size and growth by industry, the companies that lead each one, and who supplies the enzymes in the Atlas. Each figure is shown as its publisher states it; publishers define markets differently, so we never add or average them.
The whole enzyme market
By industry
Company results
About these figures
Sources
Regulatory alerts
New approvals, safety opinions, withdrawals and rule changes for enzymes, checked every week. Each alert links to the regulator's own page or the DOI. Research, not legal advice.
Watchlist Professional
Pick the enzymes and markets you follow. The list and your weekly email then show only matching alerts. This preview is saved in this browser only.
See plansLab tools
Convert activity units, work out activity from an absorbance reading, and size an enzyme dose for a batch. Everything runs in your browser; nothing is sent anywhere.
1 U = 1 µmol substrate per minute. 1 kat = 1 mol per second = 6 × 107 U.
Supplier units such as FAU, KNU, LAPU or SKB are defined by each supplier's own assay (substrate, pH, temperature, time). They have no fixed factor to U or to each other. Measure both on the same sample, then enter the factor above as a custom unit.
Activity of your enzyme sample from a change in absorbance.
How much enzyme product a batch needs, as grams, % w/w and ppm.
C₁V₁ = C₂V₂. Leave the one you want blank.
These tools do arithmetic on the numbers you enter. ε values are typical published values and change with pH, buffer and wavelength; for regulated work, use the value set in your validated method or measure a standard curve.
The platform
Five modules that take you from an enzyme to its assay, its data, and the documents you submit.
Industries, classes, profiles with chemistry, UniProt sequences and PDB structures.
ExploreEvery method per enzyme and reaction: reference, readout, conditions, unit definition, pros and cons. Filters, compare, CSV.
Open the AtlasKinetics fitted on untransformed data and ranked by AICc; lot QC with control charts and Cpk; thermal, pH and Arrhenius stability.
Open the WorkbenchStatus by market and production organism, linked to the regulator's record. US and EU first.
See marketsActivity unit converter, assay activity from absorbance or a standard curve, batch dose calculator and dilutions.
Open lab toolsDrafts development and validation reports, procedures, stability reports, CTD 3.2.S.4 and food-enzyme dossier sections from Atlas data and your results, for expert review. Exports to Word.
Open Report StudioReport Studio documents Open Report Studio →
| Document | Contents | Structured to |
|---|---|---|
| Assay development report | Method choice and rationale, conditions, kinetics, linearity, robustness | ICH Q14 |
| Validation protocol and report | Characteristics, acceptance criteria; paste results for linearity, recovery, precision ANOVA and pass/fail | ICH Q2(R2); USP <1225> |
| Analytical procedure | Reagents, standards, steps, calculations, unit definition, system suitability | CTD 3.2.S.4.2 |
| Stability report | Design, regression per batch, poolability test, shelf life from the 95% confidence bound | ICH Q1A(R2); Q5C; Q1E |
| CTD quality sections | Specification, procedures, validation, batch analyses, justification | ICH M4Q; 3.2.S.4 |
| Food enzyme dossier | Identity, source organism, manufacture, specifications, use, dietary exposure, safety studies, status elsewhere | EFSA; FDA GRAS; JECFA |
Method coverage
Plans and access
Prices in US dollars, billed annually. Items marked ◔ are in development.
- Enzyme explorer and profiles
- Assay Atlas browsing, detection map, standards index
- Source links and verification status
- Everything in Explorer
- Compare methods and export CSV
- Workbench: kinetics, assay QC, stability
- Regulatory records by enzyme
- Report Studio: development, validation, stability reports
- Everything in Professional, for the whole site
- Shared records, priority method additions
- Dossier sections: CTD and food enzyme
- Regulatory alerts
- Part 11 audit trail, e-signatures, roles; IQ/OQ/PQ package
No. It identifies the method, what it measures and its conditions, with the exact designation. Buy the current edition from the publisher to run it.
Each method shows “Reference checked” with the page where it was confirmed, or “Reference unconfirmed” until that check is done.
Not yet. Its fitting engine is tested against synthetic data with known answers. Use it for development and trending until the validation package is available.
No. It is a sourced summary of public records, each linked to the regulator's page. Confirm current status before you rely on it.